Allantoin has many beneficial effects as an active ingredient in over-the-counter cosmetics: a moisturizing and keratolytic effect, increasing the water content of the extracellular matrix and enhancing the desquamation of upper layers of dead skin cells thereby increasing the smoothness of the skin. It promotes cell proliferation and wound healing. Allantoin has a soothing, anti-irritant, and skin protectant effect by forming complexes with irritant and sensitizing agents.